Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | SLC34A1 | Q06495 | 9/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1737022 | 0.99 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11MDM2 | |
| SCHEMBL1737522 | 0.90 | MAPK14 (0.45) | MAPK14MAPK13MAPK12MAPK11MDM2 | |
| Hydrochloric Acid SCHEMBL1737777 | 0.89 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11MDM2 | |
| SCHEMBL1737149 | 0.88 | MERTK (0.38) | MAPK14MAPK13MAPK12MAPK11SLC34A1 | |
| SCHEMBL1737296 | 0.88 | MERTK (0.38) | MAPK14MAPK13MAPK12MAPK11MERTK | |
| Hydrochloric Acid SCHEMBL1736821 | 0.87 | MERTK (0.37) | MAPK14MAPK13MAPK12MAPK11SLC34A1 | |
| SCHEMBL1737411 | 0.87 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11CYP1A2 | |
| Hydrochloric Acid SCHEMBL1737406 | 0.86 | MERTK (0.38) | MAPK14MAPK13MAPK12MAPK11MDM2 | |
| SCHEMBL1736299 | 0.86 | MAPK13 (0.35) | MAPK14MAPK13MAPK12MAPK11MDM2 | |
| Hydrochloric Acid SCHEMBL1735602 | 0.86 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |