Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736821 | 0.99 | MERTK (0.37) | MERTKSLC34A1DRD4DRD3DRD2 | |
| SCHEMBL1737275 | 0.95 | ALOX5 (0.37) | MERTKSLC34A1DRD4DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL1736645 | 0.94 | ALOX5 (0.36) | MERTKSLC34A1DRD4DRD3DRD2 | |
| SCHEMBL1737522 | 0.90 | MAPK14 (0.45) | MERTKSLC34A1MAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL1737777 | 0.89 | MAPK14 (0.44) | MERTKSLC34A1MAPK13MAPK12MAPK11 | |
| SCHEMBL1737560 | 0.88 | MAPK14 (0.44) | MERTKSLC34A1KDM4CMAPK13MAPK12 | |
| SCHEMBL1737296 | 0.88 | MERTK (0.38) | MERTKDRD4DRD3DRD2MAPK13 | |
| Hydrochloric Acid SCHEMBL1737022 | 0.87 | MAPK14 (0.43) | MERTKSLC34A1KDM4CMAPK13MAPK12 | |
| SCHEMBL1735949 | 0.87 | GRIN2B (0.36) | DRD4DRD3DRD2MAPK14HTR2B | |
| Hydrochloric Acid SCHEMBL1737406 | 0.86 | MERTK (0.38) | MERTKDRD4DRD3DRD2MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |