Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17375869 | 0.85 | PSMD14 (0.64) | KMT2AKDM4EMAPK1L3MBTL1RAB9A | |
| SCHEMBL30361283 | 0.84 | KMT2A (0.48) | KMT2AKDM4EMAPK1L3MBTL1RAB9A | |
| SCHEMBL27773938 | 0.84 | CCR1 (0.54) | KMT2AKDM4EMAPK1L3MBTL1RAB9A | |
| SCHEMBL2201187 | 0.82 | KDM4E (0.55) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL2203246 | 0.82 | PSMD14 (0.51) | KMT2AKDM4EMAPK1L3MBTL1RAB9A | |
| Formaldehyde SCHEMBL27800820 | 0.82 | CCR1 (0.51) | KMT2AKDM4EMAPK1L3MBTL1RAB9A | |
| SCHEMBL4155141 | 0.81 | PSMD14 (0.50) | KMT2AKDM4EMAPK1L3MBTL1RAB9A | |
| SCHEMBL6537724 | 0.81 | PSMD14 (0.50) | KMT2AKDM4EMAPK1L3MBTL1RAB9A | |
| SCHEMBL4150906 | 0.81 | MAOB (0.53) | KMT2ARAB9AMEN1NPC1ALDH1A1 | |
| SCHEMBL430324 | 0.80 | MGAM (0.59) | KMT2AKDM4EMAPK1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015198349-A1 | A ONE POT SYNTHESIS OF 3-SUBSTITUTED QUINOLINE CARBOXYLATES AND ITS DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-30 | — | — | WO | claimed |
| WO-2015198349-A1 | A ONE POT SYNTHESIS OF 3-SUBSTITUTED QUINOLINE CARBOXYLATES AND ITS DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015198349-A1 | A ONE POT SYNTHESIS OF 3-SUBSTITUTED QUINOLINE CARBOXYLATES AND ITS DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-30 | — | — | WO | disclosed |