PSMD14 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL255348	0.49	6/20
SCHEMBL253871	0.53	5/20
SCHEMBL253706	0.58	4/20
SCHEMBL252709	0.55	4/20
SCHEMBL252287	0.51	4/20
SCHEMBL253234	0.50	3/20
Hydrochloric Acid (SCHEMBL178234)	0.93	2/20
SCHEMBL69886	0.73	2/20
SCHEMBL84954	0.71	2/20
SCHEMBL69905	0.70	2/20
SCHEMBL33593	0.69	2/20
Hydrochloric Acid (SCHEMBL45756)	0.69	2/20
SCHEMBL95883	0.68	2/20
SCHEMBL84952	0.67	2/20
SCHEMBL266633	0.61	2/20
SCHEMBL266634	0.61	2/20
SCHEMBL44666	0.59	2/20
SCHEMBL254157	0.59	2/20
SCHEMBL182930	0.59	2/20
SCHEMBL196509	0.58	2/20

Clinical trials — most relevant to PSMD14 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients	PHASE4	NOT_YET_RECRUITING
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease	PHASE4	UNKNOWN
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)	PHASE1/PHASE2	RECRUITING
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Esophageal Cancer	PHASE1	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Human Leukocyte Antigen (HLA) - A*2402 Restricted Peptide Vaccine Therapy in Patients With Advanced Gastric Cancer	PHASE1	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk	nan	NOT_YET_RECRUITING
Impact of O6-methylguanine-DNA Methyltransferase (MGMT) Promoter Methylation and MGMT Expression on Dacarbazine Treated Sarcoma Patients (MGMT)	nan	UNKNOWN
Evaluation of Proteasome as a Marker of Hepatocellular Carcinoma in Cirrhotic Patients Following Curative Treatment	nan	UNKNOWN
The Significance of Urine UbA52 In the Diagnosis of Diabetic Nephropathy	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
Autophagy Bladder Cancer	nan	UNKNOWN
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin	nan	UNKNOWN
PCD New Gene Discovery	nan	COMPLETED
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages	nan	COMPLETED
Pleiotropy and Mechanism of Peripheral Nerve Related Genes in the Progression of Amyotrophic Lateral Sclerosis	nan	UNKNOWN
Molecular Genetic Epidemiology of Endocardial Cushion Defects - SCOR in Pediatric Cardiovascular Disease	nan	COMPLETED
Implementation of Molecular Diagnostic Pathways	nan	UNKNOWN
Timecourse of Immobilization Experiment	nan	COMPLETED
Genetic Investigation of Cancer Predisposition	nan	NOT_YET_RECRUITING
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
Novel Genetic Disorders of the Immune System	nan	RECRUITING
ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study	nan	ACTIVE_NOT_RECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PSMD14 binder may also engage these)

Protein	Name	Similarity
O35593	—	1.000	O35593 →
P41878	—	1.000	P41878 →
Q9V3H2	—	1.000	Q9V3H2 →
Q9LT08	—	1.000	Q9LT08 →
Q6FKS1	—	1.000	Q6FKS1 →
P43588	—	1.000	P43588 →
O76577	—	1.000	O76577 →
Q750E9	—	1.000	Q750E9 →
Q8SQY3	—	1.000	Q8SQY3 →
Q4IJM4	—	1.000	Q4IJM4 →
COPS5	COP9 signalosome complex subunit 5	0.998	landscape →
Q86IJ1	—	0.997	Q86IJ1 →
Q6GLM9	—	0.997	Q6GLM9 →
Q9FVU9	—	0.997	Q9FVU9 →
Q6PC30	—	0.997	Q6PC30 →
P0CQ25	—	0.996	P0CQ25 →
Q7RXX8	—	0.996	Q7RXX8 →
Q6P635	—	0.996	Q6P635 →
Q8H936	—	0.995	Q8H936 →
E2AXC7	—	0.994	E2AXC7 →
O35864	—	0.994	O35864 →
P41883	—	0.993	P41883 →
P0CQ24	—	0.993	P0CQ24 →
Q9XZ58	—	0.993	Q9XZ58 →
Q54PF3	—	0.993	Q54PF3 →
Q4WZP2	—	0.992	Q4WZP2 →
Q5BBF1	—	0.992	Q5BBF1 →
B4N116	—	0.990	B4N116 →
O01974	—	0.990	O01974 →
B3MP94	—	0.990	B3MP94 →