Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1738713 | 0.99 | TP53 (0.41) | TP53MAPTALDH1A1HPGDGAA | |
| SCHEMBL1739082 | 0.94 | ALDH1A1 (0.43) | TP53MAPTALDH1A1HPGDGAA | |
| SCHEMBL1739005 | 0.94 | ALDH1A1 (0.43) | TP53MAPTALDH1A1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL1736933 | 0.93 | ALDH1A1 (0.42) | TP53MAPTALDH1A1HPGDGAA | |
| Hydrochloric Acid SCHEMBL1737348 | 0.93 | ALDH1A1 (0.42) | TP53MAPTALDH1A1HPGDALOX15 | |
| SCHEMBL1737764 | 0.92 | GAA (0.41) | TP53ALDH1A1HPGDGAAMEN1 | |
| Hydrochloric Acid SCHEMBL1735900 | 0.91 | GAA (0.40) | TP53ALDH1A1HPGDGAAMEN1 | |
| SCHEMBL1737529 | 0.91 | TP53 (0.38) | TP53ALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1736923 | 0.90 | TP53 (0.37) | TP53ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1737224 | 0.90 | TP53 (0.44) | TP53MAPTALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |