Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736548 | 0.99 | TSHR (0.35) | TSHRTNFTP53MAPTMEN1 | |
| SCHEMBL1738479 | 0.89 | TP53 (0.44) | TSHRTP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1735838 | 0.88 | TP53 (0.43) | TSHRTP53MAPTMEN1KMT2A | |
| SCHEMBL1737594 | 0.85 | HRH3 (0.41) | TP53MAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL1735552 | 0.84 | HRH3 (0.40) | TP53MAPTMEN1KMT2ALMNA | |
| SCHEMBL1737088 | 0.83 | MAPT (0.46) | TP53MAPTMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL1737118 | 0.83 | MAPT (0.45) | TP53MAPTMEN1KMT2ALMNA | |
| SCHEMBL1739295 | 0.82 | RAB9A (0.45) | TSHRTP53MAPTMEN1KMT2A | |
| SCHEMBL1737080 | 0.82 | DYRK1A (0.48) | TSHRTP53MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1737677 | 0.81 | RAB9A (0.44) | TSHRTP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |