Arcaine

Arcaine

SCHEMBL1737639

NC(N)=NCCCCN=C(N)N

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.77
ALOX15 P16050 1/20 0.77
NFKB1 P19838 1/20 0.77
MAOA P21397 1/20 0.77
MAOB P27338 1/20 0.77
DHPS P49366 1/20 0.72
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
BLM P54132 1/20 0.59
PMP22 Q01453 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1736310 0.96 DHPS (0.78) CYP1A2ALOX15NFKB1MAOAMAOB
Hydrochloric Acid SCHEMBL3139421 0.93 DHPS (0.74) CYP1A2ALOX15NFKB1MAOAMAOB
Synthalin SCHEMBL9948763 0.93 DHPS (0.74) CYP1A2ALOX15NFKB1MAOAMAOB
SCHEMBL1736351 0.92 CYP1A2 (0.67) CYP1A2ALOX15NFKB1MAOAMAOB
SCHEMBL4097449 0.87
Agmatine SCHEMBL195497 0.87
SCHEMBL6700147 0.85 DHPS (1.00) CYP1A2ALOX15NFKB1MAOAMAOB
SCHEMBL6693210 0.85 DHPS (1.00) CYP1A2ALOX15NFKB1MAOAMAOB
SCHEMBL6698306 0.85 DHPS (1.00) CYP1A2ALOX15NFKB1MAOAMAOB
Arcaine SCHEMBL3456427 0.85 BLM (0.82) CYP1A2ALOX15NFKB1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117630970-A Wind shear intelligent monitoring and early warning method based on ship-borne laser radar 中船航海科技有限责任公司 2024-03-01 CN claimed
EP-4440621-B1 PEPTIDE-DRUG CONJUGATES FOR TREATMENT OF NEURODEGENERATIVE DISEASES UNIV COPENHAGEN (DK) 2026-02-04 EP disclosed
US-20250025566-A1 PEPTIDE-DRUG CONJUGATES FOR TREATMENT OF NEURODEGENERATIVE DISEASES Københavns Universitet (DK) 2025-01-23 US disclosed
EP-4440621-A1 PEPTIDE-DRUG CONJUGATES FOR TREATMENT OF NEURODEGENERATIVE DISEASES Københavns Universitet (DK) 2024-10-09 EP disclosed
CN-118510545-A Peptide-drug conjugates for the treatment of neurodegenerative diseases 哥本哈根大学 2024-08-16 CN disclosed
EP-2989113-B1 MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS GENOMATICA INC (US) 2024-04-10 EP disclosed
WO-2023099723-A1 PEPTIDE-DRUG CONJUGATES FOR TREATMENT OF NEURODEGENERATIVE DISEASES Københavns Universitet (DK) 2023-06-08 WO disclosed
EP-3042718-A1 DEVICE FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2016-07-13 EP disclosed
US-20160122686-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-05-05 US disclosed
EP-2585420-B1 METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2016-04-06 EP disclosed
US-9127233-B2 Device and method for solubilizing, separating, removing and reacting carboxylic acids in oils, fats, aqueous or organic solutions by means of micro-or nanoemulsification Dietz, Ulrich (DE) 2015-09-08 US disclosed
EP-2585420-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION Dietz, Ulrich (DE) 2013-05-01 EP disclosed
US-20130090488-A1 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO-OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2013-04-11 US disclosed
WO-2011160857-A2 DEVICE AND METHOD FOR SOLUBILIZING, SEPARATING, REMOVING AND REACTING CARBOXYLIC ACIDS IN OILS, FATS, AQUEOUS OR ORGANIC SOLUTIONS BY MEANS OF MICRO- OR NANOEMULSIFICATION DIETZ ULRICH (DE) 2011-12-29 WO disclosed
EP-2399885-A1 Device and method for solubilizing, separating, removing and reacting carboxylic acids in aqueous or organic solutions by means of micro- or nanoemulsification Dietz, Ulrich (DE) 2011-12-28 EP disclosed
US-7718343-B2 Decomposable resin composition and pattern-forming material including the same FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20080070154-A1 DECOMPOSABLE RESIN COMPOSITION AND PATTERN-FORMING MATERIAL INCLUDING THE SAME FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed