Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736223 | 0.99 | PTGS1 (0.36) | PTGS1PTGS2POLBCSNK1DCSNK1E | |
| SCHEMBL1738894 | 0.90 | MCL1 (0.34) | KMT2AMCL1JAK2 | |
| Hydrochloric Acid SCHEMBL1736952 | 0.89 | MCL1 (0.34) | KMT2AMCL1JAK2 | |
| SCHEMBL1737425 | 0.88 | IDO1 (0.34) | POLBRAB9APDE3BPDE3AKDM4E | |
| SCHEMBL1737242 | 0.88 | NQO2 (0.35) | BCHERAB9AKMT2AMCL1KDM4E | |
| Hydrochloric Acid SCHEMBL1736304 | 0.87 | IDO1 (0.33) | RAB9APDE3BPDE3AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1737778 | 0.87 | NQO2 (0.34) | BCHEKMT2AMCL1KDM4EALDH1A1 | |
| SCHEMBL1735899 | 0.86 | KDM4E (0.33) | KDM4EALDH1A1GAAJAK2 | |
| SCHEMBL1737073 | 0.86 | CACNA1B (0.32) | JAK2 | |
| SCHEMBL1737084 | 0.86 | ALDH1A1 (0.39) | PTGS2POLBRAB9AKMT2ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |