Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918271 | 0.84 | BBOX1 (0.46) | BBOX1APP | |
| SCHEMBL18270969 | 0.83 | BBOX1 (0.37) | BBOX1APPEPHX2 | |
| SCHEMBL18270968 | 0.81 | BBOX1 (0.36) | BBOX1APPEPHX2 | |
| SCHEMBL368076 | 0.81 | BBOX1 (0.58) | BBOX1 | |
| SCHEMBL21024442 | 0.80 | CBLB (0.42) | BBOX1APPEPHX2 | |
| SCHEMBL22006989 | 0.80 | BBOX1 (0.43) | BBOX1APP | |
| SCHEMBL3381684 | 0.80 | — | — | |
| SCHEMBL13978757 | 0.79 | BBOX1 (0.37) | BBOX1APPEPHX2 | |
| SCHEMBL12210469 | 0.79 | KDM4E (0.50) | BBOX1EPHX2 | |
| SCHEMBL19170095 | 0.79 | BBOX1 (0.34) | BBOX1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7236236-B2 | Methods for detecting malaria parasites and reagent kits therefor | SYSMEX CORPORATION (JP) | 2007-06-26 | — | — | US | claimed |
| WO-2005039381-A2 | COMPOSITIONS AND PROCESSES FOR ANALYSIS OF PHARMACOLOGIC AGENTS IN BIOLOGICAL SAMPLES | DRUG RISK SOLUTIONS, L.L.C. (US) | 2005-05-06 | — | — | WO | claimed |
| US-20050042675-A1 | Solution for preparing stool specimens for diagnostic purposes | CONNEX GESELLSCHAFT ZUR OPTIMIERUNG VON FORSCHUNG UND ENTWICKLUNG MBH (DE) | 2005-02-24 | — | — | US | claimed |
| US-20050037386-A1 | Composition and processes for analysis of pharmacologic agents in biological samples | DRUG RISK SOLUTIONS, L.L.C. | 2005-02-17 | — | — | US | claimed |
| EP-0433225-B1 | Process for the production of biologically active protein (e.g. TGF) | NOVARTIS AG (CH) | 1999-04-07 | — | — | EP | claimed |
| US-5389549-A | Method for classifying leukocytes and a reagent used therefor | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1995-02-14 | — | — | US | claimed |
| US-11629154-B2 | Tetrahydropyranooxazine derivatives having selective BACE1 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2023-04-18 | — | — | US | disclosed |
| EP-3784674-B1 | TETRAHYDROPYRANOOXAZINE DERIVATIVES HAVING SELECTIVE BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2023-02-22 | — | — | EP | disclosed |
| CN-112708621-B | Sequentially-lighted multicolor DNA tetrahedral nanoprobe SLMN and preparation method and application thereof | 山东大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-113201579-B | Telomerase detection system, telomerase detection method and telomerase detection kit for targeting tumors | 山东大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-113382981-A | Disulfide compounds | 尼姆生物科技有限公司 | 2021-09-10 | — | — | CN | disclosed |
| US-20210238194-A1 | TETRAHYDROPYRANOOXAZINE DERIVATIVES HAVING SELECTIVE BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2021-08-05 | — | — | US | disclosed |
| CN-113201579-A | Telomerase detection system, telomerase detection method and telomerase detection kit for targeting tumors | 山东大学 | 2021-08-03 | — | — | CN | disclosed |
| US-5389549-A | Method for classifying leukocytes and a reagent used therefor | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0617281-A2 | A reagent for measuring immature leukocytes | TOA MEDICAL ELECTRONICS CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-5330902-A | DNA encoding a helical polypeptide attached to a gene endcoding a protein spontaneously forms inclusion bodies; purification and cleavage to separate amphilic helix from product | CREATIVE BIOMOLECULES, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5302526-A | Genetic engineering | CREATIVE BIOMOLECULES, INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5215896-A | Pendant polypeptide with amphiphilic helical structure | CREATIVE BIOMOLECULES, INC. (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0503297-A1 | GLIA activating factor and its production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5011910-A | Heptapeptides having fluorogenic and quenching groups as substrates for protease; colorimetric analysis, efficiency | WASHINGTON UNIVERSITY (US) | 1991-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11629154-B2 | Tetrahydropyranooxazine derivatives having selective BACE1 inhibitory activity | BACE1, APP, BACE2 | BBOX1 79/4885APP 2/4885EPHX2 1945/4885 |
| US-20210238194-A1 | TETRAHYDROPYRANOOXAZINE DERIVATIVES HAVING SELECTIVE BACE1 INHIBITORY ACTIVITY | BACE1, APP, BACE2 | BBOX1 79/4885APP 2/4885EPHX2 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.