SCHEMBL17377644

SCHEMBL17377644

O=C(O)CCCCCCCCCCC(CCCCCCCCCCC(=O)O)(C(=O)O)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F13A1 P00488 3/20 0.35
▸ LMNA P02545 2/20 0.34
▸ TSHR P16473 1/20 0.34
▸ NFKB1 P19838 1/20 0.34
▸ PMP22 Q01453 1/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ PTGS1 P23219 4/20 0.33
▸ PTGS2 P35354 4/20 0.33
▸ SCD O00767 1/20 0.33
▸ IMPDH1 P20839 2/20 0.33
▸ PTGER3 P43115 1/20 0.32
▸ PTGER2 P43116 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ GPR84 Q9NQS5 1/20 0.31
▸ FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22473554 1.00 F13A1 (0.35) F13A1LMNATSHRNFKB1PMP22
SCHEMBL16372007 0.94 SCD (0.44) TSHRKMT2AMEN1SCDMAPT
SCHEMBL17377639 0.90 CYP1A2 (0.47) MAPT
SCHEMBL16412299 0.90 ABCC4 (0.47) LMNAKMT2AMEN1MAPTALDH1A1
SCHEMBL22473558 0.90 ABCC4 (0.47) LMNAKMT2AMEN1MAPTALDH1A1
SCHEMBL17377640 0.87 KMT2A (0.35) F13A1LMNATSHRNFKB1PMP22
SCHEMBL17377646 0.86 KMT2A (0.39) KMT2AMEN1SCDMAPTSMN1; SMN2
SCHEMBL22473555 0.86 KMT2A (0.39) KMT2AMEN1SCDMAPTSMN1; SMN2
SCHEMBL17377636 0.84 TK2 (0.36) TSHRPTGER3MAPTRXFP1
SCHEMBL8606715 0.83 PTGER3 (0.37) F13A1LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066132-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2024-02-29 — — US disclosed
US-20240066132-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2024-02-29 — — US disclosed
US-20240066132-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2024-02-29 — — US disclosed
US-11752211-B2 Fatty acids and their use in conjugation to biomolecules NOVARTIS AG (CH) 2023-09-12 — — US disclosed
US-11752211-B2 Fatty acids and their use in conjugation to biomolecules NOVARTIS AG (CH) 2023-09-12 — — US disclosed
US-11752211-B2 Fatty acids and their use in conjugation to biomolecules NOVARTIS AG (CH) 2023-09-12 — — US disclosed
EP-3988170-A1 FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES Novartis AG (CH) 2022-04-27 — — EP disclosed
CN-114133443-A Fatty acids and their use in conjugation with biomolecules 诺华股份有限公司 2022-03-04 — — CN disclosed
CN-114099693-A Fatty acids and their use in conjugation with biomolecules 诺华股份有限公司 2022-03-01 — — CN disclosed
EP-3157571-B1 FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2021-11-24 — — EP disclosed
US-20210000964-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2021-01-07 — — US disclosed
US-10786576-B2 Fatty acids and their use in conjugation to biomolecules NOVARTIS AG (CH) 2020-09-29 — — US disclosed
US-10786576-B2 Fatty acids and their use in conjugation to biomolecules NOVARTIS AG (CH) 2020-09-29 — — US disclosed
US-10588980-B2 Fatty acids and their use in conjugation to biomolecules NOVARTIS AG (CH) 2020-03-17 — — US disclosed
US-20180326079-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2018-11-15 — — US disclosed
EP-3157571-A1 FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES Novartis AG (CH) 2017-04-26 — — EP disclosed
US-20160030585-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2016-02-04 — — US disclosed
US-20160030585-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2016-02-04 — — US disclosed
US-20160030585-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2016-02-04 — — US disclosed
WO-2015200078-A1 FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2015-12-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160030585-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES FABP1, FABP2, FABP3 F13A1 50/4885LMNA 1459/4885TSHR 828/4885
US-20240066132-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES FABP1, FABP2, FABP3 F13A1 50/4885LMNA 1459/4885TSHR 828/4885
US-11752211-B2 Fatty acids and their use in conjugation to biomolecules FABP1, FABP2, FABP3 F13A1 54/4885LMNA 1424/4885TSHR 620/4885
US-20180326079-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES FABP1, FABP2, FABP3 F13A1 50/4885LMNA 1459/4885TSHR 828/4885
US-10786576-B2 Fatty acids and their use in conjugation to biomolecules FABP1, FABP2, FABP3 F13A1 54/4885LMNA 1424/4885TSHR 620/4885
US-10588980-B2 Fatty acids and their use in conjugation to biomolecules FABP1, FABP2, FABP3 F13A1 54/4885LMNA 1424/4885TSHR 620/4885
US-20210000964-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES FABP1, FABP2, FABP3 F13A1 50/4885LMNA 1459/4885TSHR 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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