Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.35 |
| ▸ | F13A1 | P00488 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17480741 | 0.88 | ACLY (0.44) | TBXAS1CYP4F2CYP4A11TSHRPPARG | |
| SCHEMBL23978390 | 0.85 | CYP4F2 (0.41) | PRKCACYP4F2CYP4A11TSHRMEN1 | |
| SCHEMBL22473554 | 0.83 | F13A1 (0.35) | PTGER3PTGER2SCDIMPDH1F13A1 | |
| SCHEMBL17377644 | 0.83 | F13A1 (0.35) | PTGER3PTGER2SCDIMPDH1F13A1 | |
| SCHEMBL20228120 | 0.82 | CYP4F2 (0.36) | PRKCACYP4F2CYP4A11TSHRKMT2A | |
| SCHEMBL16372007 | 0.80 | SCD (0.44) | SCDTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL18723291 | 0.80 | — | — | |
| SCHEMBL25996699 | 0.79 | LTB4R (0.43) | TSHRPPARGPPARATDP1 | |
| SCHEMBL20365778 | 0.79 | CYP4F2 (0.34) | CYP4F2CYP4A11 | |
| SCHEMBL12992950 | 0.79 | ELANE (0.41) | CYP4F2CYP4A11LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998010638-A1 | THERAPEUTIC MOLECULES | AMRAD OPERATIONS PTY. LTD. (AU) | 1998-03-19 | — | — | WO | disclosed |