Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 15/20 | 0.55 |
| ▸ | ELANE | P08246 | 5/20 | 0.54 |
| ▸ | CTRC | Q99895 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853823 | 1.00 | CMA1 (0.55) | CMA1ELANECTRC | |
| SCHEMBL7556895 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL7556903 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL8136913 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL8672413 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL8136910 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL7373922 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL7456784 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL8674292 | 0.91 | ELANE (0.50) | CMA1ELANE | |
| SCHEMBL8144372 | 0.91 | ELANE (0.50) | CMA1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170144998-A1 | ELASTASE INHIBITORS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH | 2017-05-25 | — | — | US | disclosed |
| WO-2015200349-A2 | ELASTASE INHIBITORS | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144998-A1 | ELASTASE INHIBITORS | SERPINB1, ELANE, CELA1 | CMA1 25/4885ELANE 2/4885CTRC 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.