SCHEMBL173802

SCHEMBL173802

c1ccc(-n2cccn2)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
ACVR1B P36896 1/20 0.47
TGFBR1 P36897 1/20 0.47
NPC1 O15118 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GLA P06280 1/20 0.46
RAB9A P51151 1/20 0.46
ALKBH2 Q6NS38 1/20 0.46
EGLN1 Q9GZT9 1/20 0.46
KMT2A Q03164 2/20 0.45
MAPK1 P28482 1/20 0.44
NOTUM Q6P988 1/20 0.44
KDM6B O15054 1/20 0.43
PLD1 Q13393 1/20 0.41
ADORA2A P29274 1/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29635627 1.00 KDM4E (0.50) KDM4EALDH1A1LMNAACVR1BTGFBR1
Hydrochloric Acid SCHEMBL28859111 0.98 LMNA (0.49) KDM4EALDH1A1LMNAACVR1BTGFBR1
SCHEMBL27930525 0.98 LMNA (0.49) KDM4EALDH1A1LMNAACVR1BTGFBR1
SCHEMBL29616282 0.98 LMNA (0.49) KDM4EALDH1A1LMNAACVR1BTGFBR1
SCHEMBL15363768 0.98 LMNA (0.49) KDM4EALDH1A1LMNAACVR1BTGFBR1
SCHEMBL30369156 0.98 LMNA (0.49) KDM4EALDH1A1LMNAACVR1BTGFBR1
Formamide SCHEMBL2884584 0.89 LMNA (0.46) KDM4EALDH1A1LMNAACVR1BTGFBR1
SCHEMBL14182361 0.82 LMNA (0.46) KDM4EALDH1A1LMNANPC1SMN1; SMN2
SCHEMBL14763468 0.80 KDM4E (0.55) KDM4EALDH1A1LMNAACVR1BTGFBR1
SCHEMBL29959884 0.80 KDM4E (0.55) KDM4EALDH1A1LMNAACVR1BTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1041 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011050-A 2N-type cobalt complex, preparation method thereof and hydrosilylating reaction of hydrosilane and alcohol 石河子大学 2026-05-12 CN claimed
US-12256735-B2 Insecticidal combinations UPL LTD (IN) 2025-03-25 US claimed
CN-119638676-A Nitrogen heteroaromatic ring modified dibromo-1, 3-di (1-butylimidazol-3-yl) benzene ligand and preparation method thereof, iridium complex and organic electroluminescent device 清华大学深圳国际研究生院 2025-03-18 CN claimed
CN-119192180-A Iridium complex of [3,2,1-de ] acridine-5, 9-diketo quinine ligand based on aza-aromatic ring modification and organic electroluminescent device 清华大学深圳国际研究生院 2024-12-27 CN claimed
CN-118186417-A Electrochemical construction of C (sp)3)-C(sp3) Method for bonding and compound prepared by same 南开大学 2024-06-14 CN claimed
CN-115057843-B Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2024-04-30 CN claimed
CN-117836957-A Perovskite solar cell and preparation method thereof 宁德时代新能源科技股份有限公司 2024-04-05 CN claimed
CN-117623925-A Method for deoxidizing and converting photocatalytic alcohol 同济大学 2024-03-01 CN claimed
US-20240043399-A1 PYRIDINYL PYRAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) 2024-02-08 US claimed
EP-4300603-A1 PEROVSKITE SOLAR CELL AND PREPARATION METHOD THEREFOR Contemporary Amperex Technology Co., Limited (CN) 2024-01-03 EP claimed
EP-0983261-A1 SUBSTITUTED PYRIDYLPYRAZOLES AS HERBICIDES, INSECTICIDES AND ACARICIDES Bayer Aktiengesellschaft (DE) 2000-03-08 EP claimed
US-5939441-A Substituted pyridylpyrazoles BAYER AKTIENGESELLSCHAFT (DE) 1999-08-17 US claimed
WO-1998052938-A1 SUBSTITUTED PYRIDYLPYRAZOLES AS HERBICIDES, INSECTICIDES AND ACARICIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-11-26 WO claimed
EP-0846113-A1 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-06-10 EP claimed
EP-0500209-B1 Pesticidal 1-(2-pyridyl)pyrazoles RHONE POULENC AGROCHIMIE (FR) 1997-09-17 EP claimed
WO-1997007114-A1 1-(PYRIDYL)-PYRAZOLS AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-02-27 WO claimed
CN-1125727-A Substituted pyridylpyrazole compound BAYER AG (DE) 1996-07-03 CN claimed
EP-0679650-A1 Substituted pyridylpyrazoles BAYER AG (DE) 1995-11-02 EP claimed
EP-0500209-A1 Pesticidal 1-(2-pyridyl)pyrazoles RHONE-POULENC AGROCHIMIE (FR) 1992-08-26 EP claimed
CN-1063283-A 1- (2-pyridyl) pyrazole pesticide RHONE POULENC AGROCHIMIE (FR) 1992-08-05 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240043399-A1 PYRIDINYL PYRAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF PLK1, PLK2, PLK3 KDM4E 2898/4885ALDH1A1 3363/4885LMNA 2062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.