Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP2A1 | O14983 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17381178 | 1.00 | ATP2A1 (0.59) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL17380912 | 0.83 | ATP2A1 (0.78) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL17381173 | 0.83 | ATP2A1 (0.78) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL17381176 | 0.82 | ATP2A1 (0.64) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL17381115 | 0.82 | ATP2A1 (0.64) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL17381111 | 0.81 | ATP2A1 (0.50) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL20521106 | 0.76 | ATP2A1 (0.91) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL20521107 | 0.76 | ATP2A1 (0.91) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL17380894 | 0.76 | MAPT (0.41) | ATP2A1MAPTNPC1POLBMAPK1 | |
| SCHEMBL21632057 | 0.76 | ATP2A1 (0.74) | ATP2A1MAPTNPC1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197860-A2 | NOVEL THAPSIGARGIN ANALOGUES AND METHODS OF PREPARING THEM | UNIVERSITY OF COPENHAGEN (DK) | 2015-12-30 | — | — | WO | disclosed |