Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736171 | 0.99 | MAPT (0.46) | MAPTKCNH3TP53POLBALDH1A1 | |
| SCHEMBL1738308 | 0.93 | AURKA (0.44) | MAPTKCNH3TP53ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL1736916 | 0.92 | AURKA (0.43) | MAPTKCNH3TP53ALDH1A1HTT | |
| SCHEMBL1738229 | 0.90 | MAPT (0.46) | MAPTKCNH3TP53POLBALDH1A1 | |
| SCHEMBL1737194 | 0.90 | MAPT (0.39) | MAPTTP53AURKAABL1NTRK1 | |
| Hydrochloric Acid SCHEMBL1736638 | 0.89 | MAPT (0.45) | MAPTKCNH3TP53POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL1736135 | 0.89 | MAPT (0.39) | MAPTKCNH3TP53AURKAABL1 | |
| SCHEMBL1736713 | 0.89 | PTGDR2 (0.40) | MAPTTP53AURKAABL1NTRK1 | |
| SCHEMBL1737584 | 0.89 | MAPT (0.36) | MAPTTP53POLBALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL1738283 | 0.88 | PTGDR2 (0.39) | MAPTKCNH3TP53AURKAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |