Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736638 | 0.99 | MAPT (0.45) | MAPTGAAFABP4L3MBTL1NPC1 | |
| SCHEMBL1738308 | 0.91 | AURKA (0.44) | MAPTGAARAB9AMEN1KMT2A | |
| SCHEMBL1738584 | 0.91 | CCNT1 (0.40) | MAPTGAAL3MBTL1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL1736916 | 0.90 | AURKA (0.43) | MAPTGAARAB9AMEN1KMT2A | |
| SCHEMBL1738136 | 0.90 | MAPT (0.46) | MAPTGAARAB9AMEN1KMT2A | |
| SCHEMBL1737245 | 0.90 | MAPK1 (0.38) | MAPTGAAFABP4L3MBTL1RAB9A | |
| Hydrochloric Acid SCHEMBL1735321 | 0.90 | CCNT1 (0.40) | MAPTGAAL3MBTL1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL1736171 | 0.89 | MAPT (0.46) | MAPTGAARAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1737763 | 0.89 | KCNH3 (0.37) | MAPTGAAFABP4L3MBTL1RAB9A | |
| SCHEMBL1736713 | 0.88 | PTGDR2 (0.40) | MAPTGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |