Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17383179 | 0.86 | LMNA (0.43) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL17382581 | 0.86 | DDR1 (0.42) | DDR1CNR2 | |
| SCHEMBL17382576 | 0.85 | CA12 (0.32) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL27148710 | 0.85 | NPC1 (0.36) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL17383194 | 0.84 | DDR1 (0.32) | NPC1RAB9ADDR1 | |
| SCHEMBL27140601 | 0.83 | CNR2 (0.35) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL17383195 | 0.82 | UTRN (0.34) | NPC1RAB9ADDR1 | |
| SCHEMBL17383389 | 0.82 | CA12 (0.37) | NPC1RAB9ACA12CA1CA2 | |
| SCHEMBL17949520 | 0.82 | DDR1 (0.35) | DDR1 | |
| SCHEMBL17383211 | 0.77 | DDR1 (0.40) | NPC1RAB9ADDR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015198859-A1 | CONDENSED HETEROCYCLIC COMPOUND | 住友化学株式会社 | 2015-12-30 | — | — | WO | disclosed |