Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 13/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 9/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16711450 | 0.87 | CSNK1E (0.52) | CSNK1ECSNK1DGRIA1MMP13 | |
| SCHEMBL17382842 | 0.87 | CSNK1E (0.52) | CSNK1ECSNK1DGRIA1MMP13CKS1B | |
| SCHEMBL16711307 | 0.85 | CSNK1E (0.71) | CSNK1ECSNK1D | |
| SCHEMBL16711215 | 0.84 | CSNK1E (0.49) | CSNK1ECSNK1DGRIA1 | |
| SCHEMBL26645681 | 0.83 | CSNK1E (0.48) | CSNK1ECSNK1DGRIA1CKS1BSKP1 | |
| SCHEMBL17926168 | 0.82 | DPP4 (0.48) | CSNK1ECSNK1DGRIA1CKS1BSKP1 | |
| SCHEMBL30623021 | 0.79 | CSNK1E (0.44) | CSNK1ECSNK1DGRIA1CKS1BSKP1 | |
| SCHEMBL26645795 | 0.79 | CSNK1E (0.47) | CSNK1ECSNK1DGRIA1 | |
| SCHEMBL30622765 | 0.79 | CSNK1E (0.44) | CSNK1ECSNK1DGRIA1 | |
| SCHEMBL30623115 | 0.79 | CSNK1E (0.43) | CSNK1ECSNK1DGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015195880-A1 | IMIDAZO-PYRIDAZNE DERIVATIVES AS CASEIN KINASE 1 DELTA/EPSILON INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-12-23 | — | — | WO | disclosed |