Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 16/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 9/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26645020 | 0.89 | CSNK1E (0.45) | CSNK1ECSNK1DGRIA1SLC34A1 | |
| SCHEMBL26645640 | 0.89 | CSNK1E (0.44) | CSNK1ECSNK1DGRIA1SLC34A1 | |
| SCHEMBL26645681 | 0.87 | CSNK1E (0.48) | CSNK1ECSNK1DGRIA1 | |
| SCHEMBL26645306 | 0.85 | MAPK14 (0.49) | CSNK1ECSNK1D | |
| SCHEMBL26645300 | 0.85 | CSNK1E (0.43) | CSNK1ECSNK1DSLC34A1 | |
| SCHEMBL30622893 | 0.84 | CSNK1E (0.41) | CSNK1ECSNK1DGRIA1SLC34A1 | |
| SCHEMBL30623021 | 0.82 | CSNK1E (0.44) | CSNK1ECSNK1DGRIA1 | |
| 2-Aminopyridine SCHEMBL30623047 | 0.82 | CSNK1E (0.41) | CSNK1ECSNK1DSLC34A1 | |
| SCHEMBL24554177 | 0.82 | CSNK1E (0.45) | CSNK1ECSNK1DGRIA1 | |
| SCHEMBL30579563 | 0.82 | CSNK1E (0.45) | CSNK1ECSNK1DGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519265-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | Bayer Aktiengesellschaft (DE) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023213882-A1 | IRREVERSIBLE MUTEGFR INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-09 | — | — | WO | disclosed |