SCHEMBL1738296

SCHEMBL1738296

C=CCn1c(C)c(C)c2ccnc(/C=C/c3ccccc3)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
USP2 O75604 2/20 0.41
TNNI3 P19429 1/20 0.41
TNNT2 P45379 1/20 0.41
TNNC1 P63316 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
GPR35 Q9HC97 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
GLA P06280 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
MAPK1 P28482 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALDH1A1 P00352 4/20 0.37
GAA P10253 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1738297 1.00 MEN1 (0.41) MEN1KMT2AUSP2TNNI3TNNT2
Hydrochloric Acid SCHEMBL1736438 0.99 MEN1 (0.41) MEN1KMT2AUSP2TNNI3TNNT2
Hydrochloric Acid SCHEMBL1736439 0.99 MEN1 (0.41) MEN1KMT2AUSP2TNNI3TNNT2
SCHEMBL1736370 0.86 GLA (0.42) MEN1KMT2AGLAL3MBTL1NPC1
SCHEMBL1736368 0.86 GLA (0.42) MEN1KMT2AGLAL3MBTL1NPC1
Hydrochloric Acid SCHEMBL1737064 0.85 KDM4E (0.41) MEN1KMT2AGLAL3MBTL1NPC1
SCHEMBL1738550 0.84 FABP4 (0.47) MEN1KMT2AGLAL3MBTL1NPC1
SCHEMBL1737997 0.84 KDM4E (0.44) MEN1KMT2AGLAL3MBTL1NPC1
SCHEMBL1738554 0.84 FABP4 (0.47) MEN1KMT2AGLAL3MBTL1NPC1
Hydrochloric Acid SCHEMBL1736637 0.83 FABP4 (0.46) MEN1KMT2AGLAL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1784404-B1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2011-11-16 EP claimed
US-20110263306-A1 COMPUTER SYSTEM AND PROGRAM NAMCO BANDAI GAMES INC. (JP) 2011-10-27 US claimed
EP-1784404-A4 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORP (KR) 2009-09-09 EP disclosed
EP-1784404-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Yuhan Corporation (KR) 2007-05-16 EP disclosed
WO-2006025716-A1 PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO disclosed