Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.83 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.81 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.81 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.81 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | POLB | P06746 | 1/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.75 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | CA12 | O43570 | 4/20 | 0.74 |
| ▸ | CA1 | P00915 | 4/20 | 0.74 |
| ▸ | CA2 | P00918 | 4/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17383001 | 0.88 | ALDH1A1 (1.00) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL17383004 | 0.88 | CYP1A2 (0.79) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL17382815 | 0.86 | HDAC6 (1.00) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL17382809 | 0.81 | NPC1 (0.69) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL17382803 | 0.79 | HDAC6 (1.00) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL18426446 | 0.78 | CA1 (1.00) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL17383113 | 0.75 | POLB (0.70) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL17383364 | 0.74 | POLB (0.69) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL17383378 | 0.74 | HDAC6 (0.78) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 | |
| SCHEMBL20869729 | 0.74 | HDAC6 (0.72) | CYP1A2CYP2C9CYP2C19HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981920-B2 | Inhibitors of histone deacetylase | RODIN THERAPEUTICS, INC. (US) | 2018-05-29 | — | — | US | disclosed |
| US-20170204070-A1 | INHIBITORS OF HISTONE DEACETYLASE | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-07-20 | — | — | US | disclosed |
| WO-2015200619-A1 | INHIBITORS OF HISTONE DEACETYLASE | RODIN THERAPEUTICS, INC. (US) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204070-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC2, HDAC1, HDAC5 | CYP1A2 3123/4885CYP2C9 4061/4885CYP2C19 3507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.