SCHEMBL1738379

SCHEMBL1738379

COc1ccc(CSC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 7/20 0.56
▸ PPARG P37231 5/20 0.56
▸ MDM2 Q00987 2/20 0.56
▸ SLC17A5 Q9NRA2 1/20 0.56
▸ ACE P12821 3/20 0.55
▸ MDM4 O15151 2/20 0.51
▸ TP53 P04637 2/20 0.51
▸ PPARD Q03181 2/20 0.49
▸ CASP3 P42574 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28857934 1.00 PPARA (0.56) PPARAPPARGMDM2SLC17A5ACE
SCHEMBL29401307 0.91 SLC17A5 (0.61) PPARAPPARGSLC17A5ACEMDM4
SCHEMBL27620508 0.91 SLC17A5 (0.61) PPARAPPARGSLC17A5ACEMDM4
SCHEMBL119188 0.91 SLC17A5 (0.61) PPARAPPARGSLC17A5ACEMDM4
SCHEMBL29908094 0.91 SLC17A5 (0.61) PPARAPPARGSLC17A5ACEMDM4
SCHEMBL7707122 0.90 PPARA (0.55) PPARAPPARGMDM2SLC17A5ACE
SCHEMBL16634948 0.90 SLC17A5 (0.57) PPARAPPARGMDM2SLC17A5ACE
SCHEMBL29594267 0.90 SLC17A5 (0.57) PPARAPPARGMDM2SLC17A5ACE
SCHEMBL2310132 0.87 MDM2 (0.60) MDM2MDM4TP53CASP3
SCHEMBL29402409 0.87 MDM2 (0.60) MDM2MDM4TP53CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-04-30 — — US claimed
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2026-01-20 — — US claimed
CN-118255842-A Solid-liquid phase synthesis method of linaclotide 苏州特瑞药业股份有限公司 2024-06-28 — — CN claimed
US-20220249644-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2022-08-11 — — US claimed
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-04-30 — — US disclosed
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2026-01-20 — — US disclosed
CN-119708114-A Positioning cyclization method of three pairs of disulfide bonds in polypeptide synthesis process 厦门胜泽泰医药科技有限公司 2025-03-28 — — CN disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
CN-118255842-A Solid-liquid phase synthesis method of linaclotide 苏州特瑞药业股份有限公司 2024-06-28 — — CN disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116813740-A Solid phase synthesis method of cono anti-wrinkle agent 瑞博(苏州)制药有限公司 2023-09-29 — — CN disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
US-20130338085-A1 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE BIOMARCK PHARMACEUTICALS, LTD. 2013-12-19 — — US disclosed
US-8492518-B2 Mucin hypersecretion inhibitors and methods of use BIOMARCK PHARMACEUTICALS LTD. (US) 2013-07-23 — — US disclosed
US-8293870-B2 Mucin hypersecretion inhibitors and methods of use BIOMARCK PHARMACEUTICALS LTD (US) 2012-10-23 — — US disclosed
EP-2399599-A2 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE Biomarck Pharmaceuticals, Ltd. (US) 2011-12-28 — — EP disclosed
US-20100197607-A1 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE WILLIAMS, MASON L. 2010-08-05 — — US disclosed
US-20090275520-A1 MUCIN HYPERSECRETION INHIBITORS AND METHODS OF USE WILLIAMS, MASON L. 2009-11-05 — — US disclosed
US-7524926-B2 Mucin hypersecretion inhibitors and methods of use BIOMARCK PHARMACEUTICALS, LTD. (US) 2009-04-28 — — US disclosed
US-20060205664-A1 Mucin hypersecretion inhibitors and methods of use WILLIAMS, MASON L. 2006-09-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens SCN8A, SCN9A, VIP PPARA 4831/4885PPARG 4851/4885MDM2 4474/4885
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VIP, MLEC, SEC16A PPARA 3975/4885PPARG 3854/4885MDM2 3421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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