Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384062 | 0.80 | CYP19A1 (0.43) | CYP19A1POLBTBXAS1CHRNB2CHRNA7 | |
| SCHEMBL17371732 | 0.75 | SLC22A12 (0.52) | CYP19A1POLBTBXAS1CHRNB2CHRNA7 | |
| SCHEMBL243298 | 0.75 | PLAU (0.50) | — | |
| SCHEMBL17371997 | 0.74 | CYP19A1 (0.43) | CYP19A1POLBTBXAS1CHRNB2CHRNA7 | |
| SCHEMBL17371936 | 0.74 | CYP19A1 (0.60) | CYP19A1POLBCHRNB2CHRNA7CHRNA4 | |
| Hydrochloric Acid SCHEMBL7489236 | 0.73 | PLAU (0.48) | — | |
| SCHEMBL17371723 | 0.73 | CHRM1 (0.44) | CYP19A1POLBTBXAS1CHRNB2CHRNA7 | |
| SCHEMBL7113697 | 0.72 | POLB (0.74) | CYP19A1POLBCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL17372091 | 0.72 | CYP19A1 (0.44) | CYP19A1POLBTBXAS1 | |
| SCHEMBL17372069 | 0.70 | HTR2C (0.62) | CYP19A1POLBCHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015192343-A1 | P53 ACTIVATOR SMALL MOLECULES | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2015-12-23 | — | — | WO | disclosed |