Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384061 | 0.78 | HTR6 (0.45) | CYP19A1POLBHTR6TBXAS1CHRNB2 | |
| SCHEMBL17371723 | 0.77 | CHRM1 (0.44) | CYP19A1POLBHTR6TBXAS1CHRNB2 | |
| SCHEMBL17371732 | 0.77 | SLC22A12 (0.52) | CYP19A1POLBTBXAS1CHRNB2CHRNA7 | |
| SCHEMBL17372091 | 0.77 | CYP19A1 (0.44) | CYP19A1POLBHTR6TBXAS1LMNA | |
| SCHEMBL17384023 | 0.75 | CYP19A1 (0.45) | CYP19A1POLBTBXAS1CHRNB2CHRNA7 | |
| SCHEMBL17371737 | 0.74 | CYP19A1 (0.47) | CYP19A1POLBHTR6CHRNB2CHRNA7 | |
| SCHEMBL17372151 | 0.74 | CYP19A1 (0.44) | CYP19A1POLBHTR6TBXAS1CHRNB2 | |
| SCHEMBL17371898 | 0.74 | CYP19A1 (0.44) | CYP19A1POLBHTR6TBXAS1CHRNB2 | |
| SCHEMBL17384064 | 0.74 | CYP19A1 (0.44) | CYP19A1POLBMCL1TBXAS1CHRNB2 | |
| SCHEMBL17384024 | 0.73 | LMNA (0.40) | CYP19A1POLBF10HTR6TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015192343-A1 | P53 ACTIVATOR SMALL MOLECULES | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2015-12-23 | — | — | WO | disclosed |
| WO-2015192343-A1 | P53 ACTIVATOR SMALL MOLECULES | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2015-12-23 | — | — | WO | disclosed |