SCHEMBL1738519

SCHEMBL1738519

Nc1nccc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.68
ADORA2A P29274 2/20 0.65
ADORA2B P29275 2/20 0.65
DPP4 P27487 1/20 0.65
MEN1 O00255 1/20 0.65
SLC28A1 O00337 1/20 0.65
MAP3K7 O43318 1/20 0.65
SLC28A2 O43868 1/20 0.65
GAPDH P04406 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
MAPK1 P28482 1/20 0.65
ADORA1 P30542 1/20 0.65
STAT6 P42226 1/20 0.65
PI4KA P42356 1/20 0.65
KMT2A Q03164 1/20 0.65
PI4K2B Q8TCG2 1/20 0.65
DOT1L Q8TEK3 1/20 0.65
SLC29A1 Q99808 1/20 0.65
PI4K2A Q9BTU6 1/20 0.65
SLC28A3 Q9HAS3 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20418948 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL967479 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL29323163 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL20419184 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL12031134 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL17780621 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL31376058 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL11124342 1.00 SMN1; SMN2 (0.68) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
Hydrochloric Acid SCHEMBL30582654 0.99 SMN1; SMN2 (0.67) SMN1; SMN2ADORA2AADORA2BDPP4MEN1
SCHEMBL12031334 0.90 SMN1; SMN2 (0.62) SMN1; SMN2ADORA2AADORA2BDPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340848-A1 METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS PEKING UNIVERSITY (CN) 2025-11-06 US claimed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP claimed
EP-1539188-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE Merck & Co., Inc. (US) 2005-06-15 EP claimed
US-20040110717-A1 Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase MERCK SHARP & DOHME LLC 2004-06-10 US claimed
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-04-01 US claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 WO claimed
EP-0038568-B1 SYNTHESIS OF DEAZAPURINE NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1983-07-20 EP claimed
US-4347315-A FORMING 4-SUBSTITUTED 1-B-D-RIBOFURANOSYL-1H-IMIDAZO(4,5-C)PYRIDINES FROM RIBOSE-1-PHOSPHATE BURROUGHS WELLCOME CO. (US) 1982-08-31 US claimed
US-4322411-A Anti-inflammatory nucleosides BURROUGHS WELLCOME CO. (US) 1982-03-30 US claimed
EP-0038567-A1 Deazapurine nucleoside, formulations thereof, and use thereof in therapy THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-28 EP claimed
EP-0038568-A1 Synthesis of deazapurine nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-28 EP claimed
EP-4746905-A1 RSV VACCINE Astrazeneca AB (SE) 2026-05-27 EP disclosed
WO-2026104647-A1 VACCINE ASTRAZENECA AB (SE) 2026-05-21 WO disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
EP-4709417-A2 POLYNUCLEOTIDES ENCODING NOROVIRUS VP1 ANTIGENS AND USES THEREOF Merck Sharp & Dohme LLC (US) 2026-03-18 EP disclosed
US-4322411-A Anti-inflammatory nucleosides BURROUGHS WELLCOME CO. (US) 1982-03-30 US disclosed
EP-0038567-A1 Deazapurine nucleoside, formulations thereof, and use thereof in therapy THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-28 EP disclosed
EP-0038567-A1 Deazapurine nucleoside, formulations thereof, and use thereof in therapy THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-28 EP disclosed
EP-0038568-A1 Synthesis of deazapurine nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-28 EP disclosed
EP-0038568-A1 Synthesis of deazapurine nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1981-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection HAVCR2, PNP, NTPCR SMN1; SMN2 4031/4885ADORA2A 174/4885ADORA2B 541/4885
US-20040110717-A1 Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase NSUN2, NSUN3, POLRMT SMN1; SMN2 3740/4885ADORA2A 395/4885ADORA2B 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.