Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135143 | 0.85 | PTGDR2 (1.00) | PTGDR2CYP3A4PTGDR | |
| SCHEMBL17387636 | 0.81 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL135141 | 0.77 | PTGDR2 (0.84) | PTGDR2CYP3A4PTGDR | |
| SCHEMBL135081 | 0.73 | PTGDR2 (0.53) | PTGDR2CYP3A4PTGDR | |
| SCHEMBL137951 | 0.73 | PTGDR2 (1.00) | PTGDR2CYP3A4PTGDR | |
| SCHEMBL1922516 | 0.72 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL17387646 | 0.71 | PTGDR2 (0.79) | PTGDR2CYP3A4PTGDR | |
| SCHEMBL16501849 | 0.71 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL135185 | 0.71 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL156761 | 0.70 | PTGDR2 (0.68) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-B1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | BRICKELL BIOTECH INC (US) | 2016-01-06 | — | — | EP | disclosed |