Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036990 | 1.00 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL1942135 | 1.00 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL1942138 | 1.00 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL10254636 | 1.00 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL2610961 | 1.00 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL13610590 | 0.92 | ITGB3 (0.40) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL2610958 | 0.91 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL8320214 | 0.91 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL8273133 | 0.91 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 | |
| SCHEMBL1942510 | 0.91 | HDAC1 (0.41) | HDAC1HDAC8ITGB3ITGA2BHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089385-B1 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2016-01-06 | — | — | EP | disclosed |