Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | RGS4 | P49798 | 1/20 | 0.34 |
| ▸ | RGS8 | P57771 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736303 | 0.99 | DYRK1A (0.40) | DYRK1APTGDR2HRH3TDP1KDM4E | |
| SCHEMBL1738960 | 0.95 | PTGDR2 (0.40) | DYRK1APTGDR2HRH3TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL1736499 | 0.94 | PTGDR2 (0.39) | DYRK1APTGDR2HRH3TDP1KDM4E | |
| SCHEMBL1738569 | 0.93 | DYRK1A (0.40) | DYRK1APTGDR2HRH3KDM4EMAOB | |
| Hydrochloric Acid SCHEMBL1735326 | 0.92 | DYRK1A (0.39) | DYRK1APTGDR2HRH3KDM4EMAOB | |
| SCHEMBL1737469 | 0.92 | DYRK1A (0.50) | DYRK1APTGDR2TDP1KDM4EMAOA | |
| Hydrochloric Acid SCHEMBL1736451 | 0.91 | DYRK1A (0.49) | DYRK1APTGDR2TDP1KDM4EMAOA | |
| SCHEMBL1737594 | 0.90 | HRH3 (0.41) | DYRK1APTGDR2HRH3MAOBMAOA | |
| Hydrochloric Acid SCHEMBL1735552 | 0.89 | HRH3 (0.40) | DYRK1APTGDR2HRH3MAOBMAOA | |
| SCHEMBL1736377 | 0.88 | MAPT (0.41) | DYRK1AHRH3KDM4EMCL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |