SCHEMBL1739200

SCHEMBL1739200

O=C(O)c1c(CC23C=CC(CC2)C3)cccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.46
KMT2A Q03164 1/20 0.36
GRM2 Q14416 1/20 0.35
GRM3 Q14832 1/20 0.35
SLC6A2 P23975 7/20 0.33
SLC6A4 P31645 7/20 0.33
PTGER1 P34995 2/20 0.33
PTGER4 P35408 2/20 0.33
PTGER3 P43115 2/20 0.33
PTGER2 P43116 2/20 0.33
SLC6A3 Q01959 5/20 0.32
CYP2D6 P10635 3/20 0.32
FFAR4 Q5NUL3 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
KCNH2 Q12809 1/20 0.32
CYP26A1 O43174 1/20 0.32
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
HNF4A P41235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9792899 0.71 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3
SCHEMBL8872410 0.69 FOLH1 (0.70) FOLH1KMT2APTGER1PTGER4PTGER3
SCHEMBL25181448 0.68 FOLH1 (0.68) FOLH1KMT2APTGER1PTGER4PTGER3
SCHEMBL7109947 0.66 FOLH1 (0.66) FOLH1KMT2APTGER1PTGER4PTGER3
SCHEMBL5033866 0.66 FOLH1 (0.66) FOLH1KMT2ASLC6A2SLC6A4PTGER1
SCHEMBL8949856 0.66 FOLH1 (0.76) FOLH1KMT2APTGER1PTGER4PTGER3
SCHEMBL1404326 0.66 FOLH1 (0.66) FOLH1KMT2APTGER1PTGER4PTGER3
SCHEMBL593127 0.65 FOLH1 (0.61) FOLH1KMT2AHNF4A
SCHEMBL4370868 0.64 FOLH1 (1.00) FOLH1KMT2APTGER1PTGER4PTGER3
SCHEMBL25171586 0.64 FOLH1 (0.71) FOLH1KMT2APTGER1PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211514-B2 Reverse dispersion retardation film and liquid crystal display device using the same JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-07-03 US disclosed
EP-2390690-A1 INVERSELY DISPERSIVE RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JX Nippon Oil & Energy Corporation (JP) 2011-11-30 EP disclosed
EP-2060937-A1 RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME Nippon Oil Corporation (JP) 2009-05-20 EP disclosed