SCHEMBL9792899

SCHEMBL9792899

C1=CC2(Cc3ccccc3Oc3ccccc3CC34C=CC(CC3)C4)CCC1C2

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443563 0.76 MAOA (0.40)
SCHEMBL15063657 0.72 ALDH1A1 (0.34)
SCHEMBL10700252 0.70 TDP1 (0.34) SLC6A2SLC6A4SLC6A3
SCHEMBL650713 0.68 KDM1A (0.41)
SCHEMBL17912773 0.68 KCNA3 (0.39)
SCHEMBL7120876 0.67
SCHEMBL11045977 0.67 LMNA (0.30) SLC6A2SLC6A4SLC6A3
SCHEMBL11335710 0.67 HSD11B1 (0.40) SLC6A4SLC6A3
SCHEMBL9722061 0.67
SCHEMBL145956 0.65 GRIN2D (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5068296-A Crosslinked copolymers for molding materials HERCULES INCORPORATED (US) 1991-11-26 US disclosed
US-5006616-A Metathesis polymerized copolymer HERCULES INCORPORATED (US) 1991-04-09 US disclosed
US-4994535-A Molding material HERCULES INCORPORATED (US) 1991-02-19 US disclosed
US-4923943-A DICYCLOPENTADIENE, NORBORNENYL ESTERS OF NORBORNENYL ACIDS HERCULES INCORPORATED (US) 1990-05-08 US disclosed
US-4918138-A Process for producing a colored molded article of metathesis polymerized polymer HERCULES INCORPORATED (US) 1990-04-17 US disclosed
EP-0349855-A2 Molded article of metathesis polymerized polymer containing fillers and process for its preparation HERCULES INCORPORATED (US) 1990-01-10 EP disclosed
EP-0329063-A2 Process for producing a colored molded article of metathesis polymerized polymer HERCULES INCORPORATED (US) 1989-08-23 EP disclosed
EP-0305933-A2 Process for producing a molded article of metathesis polymerized polymer HERCULES INCORPORATED (US) 1989-03-08 EP disclosed
EP-0287762-A2 Methathesis polymerized copolymer HERCULES INCORPORATED (US) 1988-10-26 EP disclosed
EP-0286839-A1 Metathesis polymerized copolymer HERCULES INCORPORATED (US) 1988-10-19 EP disclosed
EP-0280247-A2 Metathesis polymerization HERCULES INCORPORATED (US) 1988-08-31 EP disclosed