SCHEMBL1739265

SCHEMBL1739265

Brc1ccc(C2CC3C=CC2C3)cc1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 11/20 0.50
MAOB P27338 5/20 0.50
RCOR1 Q9UKL0 3/20 0.50
KCNH2 Q12809 2/20 0.50
KDM1B Q8NB78 1/20 0.50
HTR2C P28335 2/20 0.44
HTR2B P41595 2/20 0.44
MAOA P21397 2/20 0.37
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6234699 0.89 KDM1A (0.38) KDM1AMAOBRCOR1KCNH2KDM1B
SCHEMBL16530012 0.89 KDM1A (0.38) KDM1AMAOBRCOR1KCNH2KDM1B
SCHEMBL21525760 0.85 KDM1A (0.42) KDM1AMAOBRCOR1KCNH2KDM1B
SCHEMBL21525759 0.85 KDM1A (0.42) KDM1AMAOBRCOR1KCNH2KDM1B
SCHEMBL912333 0.80 HTR2A (0.43) KDM1AMAOBHTR2CHTR2BMAOA
SCHEMBL1868041 0.80 KDM1A (0.50) KDM1ATDP1CYP2C9KDM4ELMNA
SCHEMBL912758 0.80 HTR2A (0.43) KDM1AHTR2CHTR2BMAPTCYP2C9
SCHEMBL12997456 0.80 KDM1A (0.36) KDM1AMAOBRCOR1KCNH2KDM1B
SCHEMBL1973918 0.79 KDM4E (0.36) HTR2CHTR2BTDP1SLC6A2SLC6A4
SCHEMBL12557101 0.79 KDM4E (0.36) HTR2CHTR2BTDP1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250177927-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITITATED MASS POLYMERIZATION PROMERUS, LLC (US) 2025-06-05 US claimed
EP-4188980-A1 POLYCYLOOLEFINIC POLYMERS AND ANION EXCHANGE MEMBRANES DERIVED THEREFROM Promerus, LLC (US) 2023-06-07 EP claimed
CN-116235324-A Polycyclic olefin polymers and anion exchange membranes derived therefrom 普罗米鲁斯有限责任公司 2023-06-06 CN claimed
WO-2022026794-A1 POLYCYLOOLEFINIC POLYMERS AND ANION EXCHANGE MEMBRANES DERIVED THEREFROM PROMERUS, LLC (US) 2022-02-03 WO claimed
US-20250177927-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITITATED MASS POLYMERIZATION PROMERUS, LLC (US) 2025-06-05 US disclosed
WO-2024137739-A1 SUPPORTED MEMBRANES BY THERMAL AND UV INITIATED MASS POLYMERIZATION PROMERUS, LLC (US) 2024-06-27 WO disclosed
EP-4188980-A1 POLYCYLOOLEFINIC POLYMERS AND ANION EXCHANGE MEMBRANES DERIVED THEREFROM Promerus, LLC (US) 2023-06-07 EP disclosed
CN-116235324-A Polycyclic olefin polymers and anion exchange membranes derived therefrom 普罗米鲁斯有限责任公司 2023-06-06 CN disclosed
WO-2022026794-A1 POLYCYLOOLEFINIC POLYMERS AND ANION EXCHANGE MEMBRANES DERIVED THEREFROM PROMERUS, LLC (US) 2022-02-03 WO disclosed
WO-2022026794-A1 POLYCYLOOLEFINIC POLYMERS AND ANION EXCHANGE MEMBRANES DERIVED THEREFROM PROMERUS, LLC (US) 2022-02-03 WO disclosed
EP-2390690-A1 INVERSELY DISPERSIVE RETARDATION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JX Nippon Oil & Energy Corporation (JP) 2011-11-30 EP disclosed