⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621790 | 0.83 | — | — | |
| SCHEMBL619733 | 0.73 | SLC6A2 (0.30) | — | |
| SCHEMBL621707 | 0.72 | GPR119 (0.37) | — | |
| SCHEMBL27694805 | 0.72 | — | — | |
| SCHEMBL622081 | 0.71 | — | — | |
| SCHEMBL27676094 | 0.71 | — | — | |
| SCHEMBL566655 | 0.70 | — | — | |
| SCHEMBL567080 | 0.70 | — | — | |
| SCHEMBL6028481 | 0.69 | — | — | |
| SCHEMBL7070978 | 0.69 | GAA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389376-A1 | NOVEL BICYCLIC ANTIBIOTICS | Basilea Pharmaceutica AG (CH) | 2011-11-30 | — | — | EP | disclosed |
| WO-2010084152-A1 | NOVEL BICYCLIC ANTIBIOTICS | BASILEA PHARMACEUTICA AG (CH) | 2010-07-29 | — | — | WO | disclosed |