Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736265 | 0.99 | MAPT (0.42) | MAPTPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1737165 | 0.89 | FABP4 (0.44) | MAPTSMN1; SMN2THRBTP53POLB | |
| Hydrochloric Acid SCHEMBL1737555 | 0.88 | FABP4 (0.43) | MAPTSMN1; SMN2THRBTP53POLB | |
| SCHEMBL1737139 | 0.87 | MAPT (0.45) | MAPTSMN1; SMN2THRBTP53HTT | |
| Hydrochloric Acid SCHEMBL1736158 | 0.86 | MAPT (0.44) | MAPTTHRBTP53 | |
| SCHEMBL1736758 | 0.85 | MAOB (0.44) | MAPTTHRBTP53 | |
| SCHEMBL1737357 | 0.85 | MCL1 (0.40) | MAPTSMN1; SMN2TP53HTT | |
| SCHEMBL1738542 | 0.85 | MCL1 (0.40) | MAPTSMN1; SMN2TP53POLBHTT | |
| SCHEMBL1737098 | 0.85 | TP53 (0.40) | MAPTTHRBTP53CSF1R | |
| Hydrochloric Acid SCHEMBL1735348 | 0.85 | MAOB (0.43) | MAPTTHRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-B1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2011-11-16 | — | — | EP | claimed |
| US-20110263306-A1 | COMPUTER SYSTEM AND PROGRAM | NAMCO BANDAI GAMES INC. (JP) | 2011-10-27 | — | — | US | claimed |