Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.72 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.72 |
| ▸ | S1PR2 | O95136 | 12/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.61 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.53 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL17394576 | 0.92 | LPAR3 (0.72) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL7125340 | 0.90 | LPAR3 (0.75) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL17394581 | 0.87 | LPAR3 (0.53) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| Trolamine SCHEMBL9576536 | 0.86 | LPAR3 (0.69) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL19512203 | 0.86 | LPAR3 (0.75) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| Trimethylammonium SCHEMBL17394578 | 0.85 | LPAR3 (0.82) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL29141158 | 0.85 | LPAR3 (0.90) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| Bromide SCHEMBL29141160 | 0.85 | LPAR3 (0.90) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL23534144 | 0.85 | LPAR3 (1.00) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL307332 | 0.85 | LPAR3 (1.00) | LPAR3LPAR2S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240125733-A1 | SURFACE TREATMENT OF SEMICONDUCTOR SENSORS | Life Technologies Corporation | 2024-04-18 | — | — | US | disclosed |
| US-11782019-B2 | Surface treatment of semiconductor sensors | Life Technologies Corporation (US) | 2023-10-10 | — | — | US | disclosed |
| EP-3653728-B1 | METHODS, SYSTEMS, COMPOSITIONS, KITS, APPARATUS AND COMPUTER-READABLE MEDIA FOR MOLECULAR TAGGING | LIFE TECHNOLOGIES CORP (US) | 2023-02-01 | — | — | EP | disclosed |
| US-20210363596-A1 | Methods, Systems, Compositions, Kits, Apparatus and Computer-Readable Media for Molecular Tagging | Life Technologies Corporation | 2021-11-25 | — | — | US | disclosed |
| US-11124842-B2 | Methods, systems, compositions, kits, apparatus and computer-readable media for molecular tagging | Life Technologies Corporation (US) | 2021-09-21 | — | — | US | disclosed |
| US-11091811-B2 | — | — | 2021-08-17 | — | — | US | disclosed |
| US-20210102916-A1 | SURFACE TREATMENT OF SEMICONDUCTOR SENSORS | Life Technologies Corporation (US) | 2021-04-08 | — | — | US | disclosed |
| US-10809225-B2 | Surface treatment of semiconductor sensors | Life Technologies Corporation (US) | 2020-10-20 | — | — | US | disclosed |
| EP-3653728-A1 | METHODS, SYSTEMS, COMPOSITIONS, KITS, APPARATUS AND COMPUTER-READABLE MEDIA FOR MOLECULAR TAGGING | Life Technologies Corporation (US) | 2020-05-20 | — | — | EP | disclosed |
| US-20190323091-A1 | METHODS, SYSTEMS, COMPOSITIONS, KITS, APPARATUS AND COMPUTER-READABLE MEDIA FOR MOLECULAR TAGGING | Life Technologies Corporation | 2019-10-24 | — | — | US | disclosed |
| EP-3307908-B1 | METHODS FOR MOLECULAR TAGGING | LIFE TECHNOLOGIES CORP (US) | 2019-09-11 | — | — | EP | disclosed |
| US-10344336-B2 | Methods, systems, compositions, kits, apparatus and computer-readable media for molecular tagging | Life Technologies Corporation (US) | 2019-07-09 | — | — | US | disclosed |
| EP-3307908-A1 | METHODS, SYSTEMS, COMPOSITIONS, KITS, APPARATUS AND COMPUTER-READABLE MEDIA FOR MOLECULAR TAGGING | Life Technologies Corporation (US) | 2018-04-18 | — | — | EP | disclosed |
| EP-3164701-A1 | SURFACE TREATMENT OF SEMICONDUCTOR SENSORS | Life Technologies Corporation (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016201142-A1 | METHODS, SYSTEMS, COMPOSITIONS, KITS, APPARATUS AND COMPUTER-READABLE MEDIA FOR MOLECULAR TAGGING | Life Technologies Corporation (US) | 2016-12-15 | — | — | WO | disclosed |
| US-20160362748-A1 | METHODS, SYSTEMS, COMPOSITIONS, KITS, APPARATUS AND COMPUTER-READABLE MEDIA FOR MOLECULAR TAGGING | Life Technologies Corporation | 2016-12-15 | — | — | US | disclosed |
| WO-2016004244-A1 | SURFACE TREATMENT OF SEMICONDUCTOR SENSORS | Life Technologies Corporation (US) | 2016-01-07 | — | — | WO | disclosed |
| US-20160003768-A1 | SURFACE TREATMENT OF SEMICONDUCTOR SENSORS | Life Technologies Corporation | 2016-01-07 | — | — | US | disclosed |