Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.65 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.64 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.64 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.64 |
| ▸ | PHF8 | Q9UPP1 | 7/20 | 0.52 |
| ▸ | KDM2A | Q9Y2K7 | 7/20 | 0.52 |
| ▸ | KDM5C | P41229 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KDM6B | O15054 | 3/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL11059037 | 1.00 | LMNA (0.65) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL27300801 | 0.97 | LMNA (0.61) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL8719349 | 0.97 | LMNA (0.61) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL15518071 | 0.97 | LMNA (0.61) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL8720118 | 0.94 | LMNA (0.58) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28044411 | 0.94 | LMNA (0.58) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28454559 | 0.91 | LMNA (0.55) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28454927 | 0.91 | LMNA (0.55) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28177178 | 0.91 | LMNA (0.55) | LMNASLC15A2EGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28135272 | 0.91 | LMNA (0.55) | LMNASLC15A2EGLN1ALKBH5SUCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1834 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116355676-B | Composite antioxidant for prolonging induction period of lubricating oil and preparation method thereof | 江西亮华科技有限公司 | 2024-10-01 | — | — | CN | claimed |
| US-20240218284-A1 | Method for Reduction of Abnormal Combustion Events | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-07-04 | — | — | US | claimed |
| CN-118207049-A | High-foam heavy oil pollution spray cleaning agent and preparation method thereof | 山立欣业新材料(广东)有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-116554946-B | Modified fullerene hot-rolling lubricant and preparation method and application thereof | 奎克化学（中国）有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117925294-A | Neutral alkylbenzene sulfonate additive and preparation method thereof | 中国石油天然气股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117866689-A | Environment-friendly water-based cold extrusion lubricant and preparation method and application thereof | 大庆市盛日石油技术开发有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-113861031-B | Ester compound, preparation method and application thereof, and lubricating oil composition | 中国石油化工股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117801854-A | Fuel oil detergent composition and preparation method thereof | 比亚迪股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117757554-A | Lubricating oil with wear resistance and stability | 正大国际科技(常德)集团有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117736055-A | Special emulsion explosive for high-altitude low-temperature low-pressure environment and preparation method thereof | 四川雅化民爆集团有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-0258400-A1 | FUNCTIONAL FLUID WITH BORATED EPOXIDES, CARBOYLIC SOLUBILIZERS, ZINC SALTS, AND CALCIUM COMPLEXES. | LUBRIZOL CORP (US) | 1988-03-09 | — | — | EP | claimed |
| US-4710248-A | IMMISCIBLE OXIDIZER PHASE DISPERSED IN FUEL PHASE CONTAINING HYDROPHILIC, LIPOPHILIC MODIFIER | ICI AUSTRALIA LIMITED (AU) | 1987-12-01 | — | — | US | claimed |
| CN-87100657-A | Working fluid with boracic epoxide, carboxylic solubilizers, zinc salt and calcium complexes | — | 1987-09-23 | — | — | CN | claimed |
| WO-1987005046-A1 | FUNCTIONAL FLUID WITH BORATED EPOXIDES, CARBOYLIC SOLUBILIZERS, ZINC SALTS, AND CALCIUM COMPLEXES | THE LUBRIZOL CORPORATION (US) | 1987-08-27 | — | — | WO | claimed |
| EP-0213786-A1 | Emulsion explosive compositions and a process of making the same | ICI AUSTRALIA LIMITED (AU) | 1987-03-11 | — | — | EP | claimed |
| US-4533723-A | Semi-esters of polyisobutylenesuccinic acid, their synthesis and preparations containing these compounds which can be transformed by radiation into an adhesive | TH. GOLDSCHMIDT AG (DE) | 1985-08-06 | — | — | US | claimed |
| EP-0031236-B1 | LUBRICANT ADDITIVES, THEIR METHOD OF PREPARATION AND LUBRICANTS CONTAINING THEM | The British Petroleum Company p.l.c. (GB) | 1984-01-25 | — | — | EP | claimed |
| EP-0031236-A2 | Lubricant additives, their method of preparation and lubricants containing them | The British Petroleum Company p.l.c. (GB) | 1981-07-01 | — | — | EP | claimed |
| US-3990979-A | Low ash antirust dispersant additive | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1976-11-09 | — | — | US | claimed |
| US-3957855-A | FUEL ADDITIVES, LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 1976-05-18 | — | — | US | claimed |