Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KLK7 | P49862 | 2/20 | 0.60 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.60 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21715246 | 0.94 | MAPT (0.56) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL29627360 | 0.94 | MAPT (0.56) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL21715270 | 0.91 | MAPT (0.53) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL21543748 | 0.91 | MAPT (0.55) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL31276873 | 0.90 | MAPT (0.54) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL18942773 | 0.90 | MAPT (0.64) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL16762121 | 0.90 | CTSK (0.53) | MAPTKLK7KLK5 | |
| SCHEMBL21543552 | 0.89 | MAPT (0.57) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL3951637 | 0.88 | MAPT (0.51) | MAPTKLK7KLK5ITGB3ITGA2B | |
| SCHEMBL29627379 | 0.88 | MAPT (0.54) | MAPTKLK7KLK5ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164127-A1 | COMPOSITIONS AND METHODS TO IMPROVE ADOPTIVE CELL THERAPIES | 7 HILLS INTERESTS, LLC (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016003980-A1 | COMPOSITIONS AND METHODS TO IMPROVE ADOPTIVE CELL THERAPIES | 7 HILLS INTERESTS LLC (US) | 2016-01-07 | — | — | WO | disclosed |