Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 8/20 | 0.66 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | RPA1 | P27694 | 2/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.44 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738076 | 0.86 | MARS1 (0.64) | MARS1RPA1MALT1L3MBTL1 | |
| SCHEMBL1738070 | 0.84 | MARS1 (0.53) | MARS1KMOP2RY14RPA1SLC16A3 | |
| SCHEMBL14758758 | 0.82 | PPP1CA (0.56) | MARS1PPP1CAKMORPA1L3MBTL1 | |
| SCHEMBL117705 | 0.80 | MARS1 (1.00) | MARS1RPA1 | |
| SCHEMBL1765063 | 0.78 | PPP1CA (0.82) | MARS1PPP1CARPA1L3MBTL1 | |
| SCHEMBL1739614 | 0.77 | MARS1 (0.60) | MARS1PPP1CAP2RY14RPA1MALT1 | |
| SCHEMBL1738072 | 0.76 | MARS1 (0.63) | MARS1PPP1CAP2RY14 | |
| SCHEMBL1765047 | 0.76 | PPP1CA (0.78) | MARS1PPP1CARPA1MALT1L3MBTL1 | |
| SCHEMBL4692489 | 0.74 | MARS1 (0.60) | MARS1RPA1MALT1L3MBTL1 | |
| SCHEMBL1739427 | 0.74 | MARS1 (0.60) | MARS1RPA1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390252-A1 | New pyrazole derivatives | Almirall, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |