Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ITGAM | P11215 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740272 | 1.00 | FBP1 (0.40) | FBP1KMT2AMAPTAPPSNCA | |
| SCHEMBL1740259 | 0.90 | FBP1 (0.50) | FBP1KMT2AMAPTAPPSNCA | |
| SCHEMBL1740258 | 0.90 | FBP1 (0.50) | FBP1KMT2AMAPTAPPSNCA | |
| SCHEMBL1738979 | 0.86 | KMT2A (0.34) | FBP1KMT2AMAPTAPPSNCA | |
| SCHEMBL7839339 | 0.85 | FBP1 (0.46) | FBP1MAPTAPPSNCATSHR | |
| SCHEMBL2422274 | 0.85 | FBP1 (0.45) | FBP1KMT2AMAPTAPPSNCA | |
| SCHEMBL2422277 | 0.85 | FBP1 (0.45) | FBP1KMT2AMAPTAPPSNCA | |
| SCHEMBL4219230 | 0.83 | FBP1 (0.39) | FBP1KMT2AMAPTTSHRABCB11 | |
| SCHEMBL3711852 | 0.83 | FBP1 (0.39) | FBP1KMT2AMAPTTSHRABCB11 | |
| SCHEMBL699507 | 0.82 | FBP1 (0.38) | FBP1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389381-A1 | SPIROINDOLINONE DERIVATIVE PRODRUGS | F. Hoffmann-La Roche AG (CH) | 2011-11-30 | — | — | EP | disclosed |
| US-8038247-B2 | Recording apparatus and recording method | CANON KABUSHIKI KAISHA (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010084097-A1 | SPIROINDOLINONE DERIVATIVE PRODRUGS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-07-29 | — | — | WO | disclosed |