Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MTOR | P42345 | 6/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17400776 | 0.96 | MEN1 (0.48) | CACNA1HMEN1KMT2AMTORPIK3CA | |
| SCHEMBL7875944 | 0.85 | TP53 (0.53) | CACNA1HMEN1KMT2AMTORPIK3CA | |
| SCHEMBL17400807 | 0.78 | CPS1 (0.54) | MTORPIK3CA | |
| SCHEMBL17400787 | 0.77 | MAP2K2 (0.60) | MEN1KMT2AKDM4ETSHRLMNA | |
| SCHEMBL21516880 | 0.75 | MAP2K1 (0.50) | MEN1KMT2AKDM4E | |
| SCHEMBL20460502 | 0.74 | HPGD (0.58) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15651904 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL17400772 | 0.73 | CPS1 (0.56) | KDM4ETSHRLMNA | |
| SCHEMBL399815 | 0.73 | CACNA1H (0.54) | CACNA1HMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL399814 | 0.73 | CACNA1H (0.54) | CACNA1HMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421846-B1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INT (DE) | 2016-01-06 | — | — | EP | disclosed |