Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13264467 | 0.81 | PTPN11 (0.46) | TSHRMAOBMAOAPPARGPPARD | |
| SCHEMBL29409545 | 0.71 | MAOB (0.67) | MAPK14MAOBMAOACA12CA1 | |
| SCHEMBL4210087 | 0.71 | MAOB (0.55) | MAOBMAOAFFAR1 | |
| SCHEMBL4206758 | 0.71 | MAOB (0.52) | MAOBMAOA | |
| SCHEMBL4211790 | 0.67 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL4211558 | 0.67 | MAOB (0.57) | MAOBMAOA | |
| SCHEMBL7153441 | 0.66 | POLB (0.56) | — | |
| SCHEMBL5858887 | 0.65 | HSD17B10 (0.59) | TSHRMAPK14MAOBMAOACA12 | |
| SCHEMBL4321060 | 0.65 | MAOB (0.68) | TSHRMAOBMAOA | |
| SCHEMBL4328943 | 0.65 | MAOB (0.68) | TSHRMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160003836-A1 | PHOTO OR CHEMOLABILE CONJUGATES FOR MOLECULES DETECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2016-01-07 | — | — | US | disclosed |