Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL10898008 | 0.96 | POLB (0.53) | POLBGAASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9826297 | 0.91 | POLB (0.54) | POLBGAASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9826466 | 0.88 | GAA (0.54) | POLBGAASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10934516 | 0.88 | GAA (0.54) | POLBGAASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL2628192 | 0.87 | ALDH1A1 (0.58) | POLBGAASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL2628204 | 0.87 | ALDH1A1 (0.58) | POLBGAASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL9632476 | 0.85 | LMNA (0.60) | POLBSMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL8347541 | 0.85 | KDM4E (0.68) | POLBSMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL22066521 | 0.84 | LMNA (0.55) | POLBSMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL21483718 | 0.84 | POLB (0.54) | POLBGAASMN1; SMN2KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030143701-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. | 2003-07-31 | — | — | US | disclosed |
| EP-0924194-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-05-14 | — | — | EP | disclosed |
| US-6528686-B1 | Reacting primary amine and ketone functionalized derivatives; catalytically reducing | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-0924193-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-0939134-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0654534-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2000-03-01 | — | — | EP | disclosed |
| EP-0939134-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0924194-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0924193-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0259750-A2 | Aryl ethanol amines, process for their preparation and their use as growth promotors | BAYER AG (DE) | 1988-03-16 | — | — | EP | disclosed |
| EP-0239815-A1 | Substituted thiazoles and oxazoles, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |
| EP-0070133-B1 | SECONDARY PHENYLETHANOL AMINES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATION | BEECHAM GROUP PLC (GB) | 1986-05-14 | — | — | EP | disclosed |
| EP-0052963-B1 | SECONDARY AMINES | BEECHAM GROUP PLC (GB) | 1985-02-20 | — | — | EP | disclosed |
| EP-0118489-A1 | SECONDARY ARYLETHANOLAMINES | BEECHAM GROUP PLC (GB) | 1984-09-19 | — | — | EP | disclosed |
| WO-1984000956-A1 | SECONDARY ARYLETHANOLAMINES | BEECHAM GROUP PLC (GB) | 1984-03-15 | — | — | WO | disclosed |
| EP-0102213-A1 | Ethanolamine derivatives, pharmaceutical compositions containing them, and processes for preparing them | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4382958-A | Secondary amines and compositions for treatment of hypoglycaemia or obesity | BEECHAM GROUP LIMITED (GB) | 1983-05-10 | — | — | US | disclosed |
| EP-0070133-A2 | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application | BEECHAM GROUP PLC (GB) | 1983-01-19 | — | — | EP | disclosed |
| EP-0052963-A1 | Secondary amines | BEECHAM GROUP PLC (GB) | 1982-06-02 | — | — | EP | disclosed |