Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783253 | 0.72 | ALDH1A1 (0.67) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL14979273 | 0.72 | KDM4E (0.48) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL710428 | 0.72 | ALDH1A1 (0.67) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL710138 | 0.71 | KDM4E (0.46) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL14979244 | 0.69 | KDM4E (0.44) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL708661 | 0.69 | ALDH1A1 (0.62) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL6125325 | 0.69 | ALDH1A1 (0.62) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL710523 | 0.69 | ALDH1A1 (0.62) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL710509 | 0.67 | ALDH1A1 (0.56) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL13285283 | 0.61 | ALDH1A1 (0.69) | KDM4EMEN1ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389379-A1 | Poly (ADP-Ribose) Polymerase (PARP) Inhibitors | Takeda Pharmaceutical Company Limited (JP) | 2011-11-30 | — | — | EP | claimed |
| WO-2010085570-A1 | Poly (ADP-Ribose) Polymerase (PARP) Inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-07-29 | — | — | WO | claimed |