Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | THRB | P10828 | 8/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | HTT | P42858 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.72 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.72 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | CHN2 | P52757 | 1/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 6/20 | 0.58 |
| ▸ | BLM | P54132 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.58 |
| ▸ | TOP2A | P11388 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17404467 | 1.00 | MEN1 (0.72) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17949135 | 0.99 | MEN1 (0.72) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17928804 | 0.99 | MEN1 (0.72) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17928783 | 0.98 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929848 | 0.98 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929840 | 0.98 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929846 | 0.98 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929844 | 0.98 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929845 | 0.98 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL9607884 | 0.97 | MEN1 (0.70) | MEN1THRBKMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004048-A2 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | BLEND THERAPEUTICS, INC. (US) | 2016-01-07 | — | — | WO | disclosed |