Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.70 |
| ▸ | THRB | P10828 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | HTT | P42858 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.70 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.70 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | RECQL | P46063 | 6/20 | 0.59 |
| ▸ | BLM | P54132 | 6/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.59 |
| ▸ | TOP2A | P11388 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17929838 | 1.00 | MEN1 (0.70) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17928804 | 0.97 | MEN1 (0.72) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17404467 | 0.97 | MEN1 (0.72) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17949135 | 0.97 | MEN1 (0.72) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17404752 | 0.97 | MEN1 (0.72) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929846 | 0.96 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929844 | 0.96 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929845 | 0.96 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17929848 | 0.96 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA | |
| SCHEMBL17928783 | 0.96 | MEN1 (0.71) | MEN1THRBKMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828925-B2 | Etoposide and doxorubicin conjugates for drug delivery | ANGIOCHEM INC. (CA) | 2014-09-09 | — | — | US | disclosed |
| US-8828925-B2 | Etoposide and doxorubicin conjugates for drug delivery | ANGIOCHEM INC. (CA) | 2014-09-09 | — | — | US | disclosed |
| US-20120135914-A1 | ETOPOSIDE AND DOXORUBICIN CONJUGATES FOR DRUG DELIVERY | ANGIOCHEM INC. (CA) | 2012-05-31 | — | — | US | disclosed |
| US-20120135914-A1 | ETOPOSIDE AND DOXORUBICIN CONJUGATES FOR DRUG DELIVERY | ANGIOCHEM INC. (CA) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135914-A1 | ETOPOSIDE AND DOXORUBICIN CONJUGATES FOR DRUG DELIVERY | GLS, AQP4, ABCB1 | MEN1 582/4885THRB 4818/4885KMT2A 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.