SCHEMBL17409131

SCHEMBL17409131

COc1c(C(C)(C)C)cc2c(c1-c1cc(C(C)(C)C)cc(C(C)(C)C)c1)C=C(C)C2[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17409306 0.85 PDE4B (0.37)
Hydrochloric Acid SCHEMBL30395172 0.84
Hydrochloric Acid SCHEMBL29949511 0.84
SCHEMBL20165789 0.83 PTGS2 (0.31)
SCHEMBL21451181 0.83 PTGS1 (0.31)
SCHEMBL29873709 0.83 PTGS2 (0.31)
SCHEMBL14645995 0.81 PTGS2 (0.30)
SCHEMBL18772405 0.81 PTGS1 (0.30)
Hydrochloric Acid SCHEMBL21433873 0.80
Hydrochloric Acid SCHEMBL29873974 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469699-B2 Catalysts BOREALIS AG (AT) 2016-10-18 US disclosed
US-20160024123-A1 Asymmetrical Ligands BOREALIS AG (AT) 2016-01-28 US disclosed
US-20160002369-A1 CATALYSTS BOREALIS AG (AT) 2016-01-07 US disclosed