Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17419714 | 0.96 | GLS (0.91) | GLS | |
| SCHEMBL29752915 | 0.96 | GLS (0.91) | GLS | |
| SCHEMBL17412076 | 0.92 | GLS (0.83) | GLS | |
| SCHEMBL17411710 | 0.92 | GLS (0.86) | GLS | |
| SCHEMBL17412045 | 0.92 | GLS (0.81) | GLS | |
| SCHEMBL17419954 | 0.91 | GLS (1.00) | GLS | |
| SCHEMBL17412040 | 0.91 | GLS (1.00) | GLS | |
| SCHEMBL29753027 | 0.91 | GLS (1.00) | GLS | |
| SCHEMBL17396704 | 0.91 | GLS (1.00) | GLS | |
| SCHEMBL17411595 | 0.91 | GLS (0.86) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9809588-B2 | GLS1 inhibitors for treating disease | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2017-11-07 | — | — | US | disclosed |
| WO-2016004404-A2 | GLS1 INHIBITORS FOR TREATING DISEASE | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2016-01-07 | — | — | WO | disclosed |