SCHEMBL17412413

SCHEMBL17412413

Clc1cc(-c2ccccc2)nc(-c2cc3cccc4ccc5cccc2c5c43)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.45
HSP90AA1 P07900 1/20 0.45
HSP90AB1 P08238 1/20 0.45
CYP1A2 P05177 2/20 0.41
ACHE P22303 2/20 0.41
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41
AHR P35869 1/20 0.41
ALDH1A1 P00352 5/20 0.40
HPGD P15428 5/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
PTGES O14684 1/20 0.38
HSD17B10 Q99714 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17412418 0.88 CYP1A2 (0.42) KDM4EHSP90AA1HSP90AB1CYP1A2ACHE
SCHEMBL17412390 0.84 KDM4E (0.51) KDM4EHSP90AA1HSP90AB1ACHEALDH1A1
SCHEMBL17083462 0.82 CYP1A2 (0.42) KDM4ECYP1A2ACHEERBB2FYN
SCHEMBL29750648 0.81 KDM4E (0.51) KDM4EHSP90AA1HSP90AB1CYP1A2ACHE
SCHEMBL17412427 0.81 KDM4E (0.51) KDM4EHSP90AA1HSP90AB1CYP1A2ACHE
SCHEMBL17412377 0.81 LMNA (0.51) KDM4EHSP90AA1HSP90AB1ALDH1A1HPGD
SCHEMBL17427682 0.79 CYP1A2 (0.44) KDM4ECYP1A2ACHEERBB2FYN
SCHEMBL24211950 0.78 KDM4E (0.49) KDM4EHSP90AA1HSP90AB1CYP1A2ALDH1A1
SCHEMBL17083459 0.78 CYP1A2 (0.49) KDM4ECYP1A2ACHEERBB2FYN
SCHEMBL25112823 0.78 CYP1A2 (0.47) KDM4ECYP1A2ACHEERBB2FYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016003225-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-01-07 WO disclosed