Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.44 |
| ▸ | MPL | P40238 | 8/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17400609 | 0.91 | ADORA3 (0.43) | ADORA3MPLTRPV4NEK2PDE4A | |
| SCHEMBL17400491 | 0.91 | MPL (0.44) | ADORA3MPLTRPV4NEK2PDE4A | |
| SCHEMBL17412954 | 0.90 | ADORA3 (0.43) | ADORA3MPLTRPV4NEK2PDE4A | |
| SCHEMBL17412717 | 0.89 | MPL (0.43) | ADORA3MPLTRPV4NEK2 | |
| SCHEMBL17412748 | 0.89 | MPL (0.42) | ADORA3MPL | |
| SCHEMBL17412771 | 0.89 | ADORA3 (0.39) | ADORA3MPLTRPV4 | |
| SCHEMBL17400703 | 0.88 | MPL (0.42) | ADORA3MPLTRPV4NEK2 | |
| SCHEMBL17400550 | 0.88 | ADORA3 (0.41) | ADORA3MPLTRPV4NEK2 | |
| SCHEMBL17412711 | 0.87 | MPL (0.42) | ADORA3MPLTRPV4 | |
| SCHEMBL17400563 | 0.87 | MPL (0.44) | ADORA3MPLPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9562044-B2 | 2-acylaminothiazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20160002218-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002218-A1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF | CHRM3, CHRM2, CHRM5 | ADORA3 56/4885MPL 3292/4885TRPV4 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.