Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.54 |
| ▸ | ITK | Q08881 | 6/20 | 0.54 |
| ▸ | PLCG1 | P19174 | 11/20 | 0.49 |
| ▸ | JAK3 | P52333 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17412986 | 0.93 | PLCG1 (0.59) | BTKITKPLCG1JAK3 | |
| SCHEMBL17412951 | 0.90 | PLCG1 (0.59) | BTKITKPLCG1JAK3 | |
| SCHEMBL17413093 | 0.89 | BTK (0.47) | BTKITKPLCG1JAK3 | |
| SCHEMBL17412953 | 0.84 | BTK (0.51) | BTKITKPLCG1JAK3 | |
| SCHEMBL17413001 | 0.82 | MAPK1 (0.52) | BTKITKPLCG1JAK3 | |
| SCHEMBL17413199 | 0.78 | PLCG1 (0.49) | BTKITKPLCG1JAK3 | |
| SCHEMBL17413094 | 0.77 | BTK (0.43) | BTKITKPLCG1JAK3 | |
| SCHEMBL17413002 | 0.77 | ITK (0.51) | BTKITKPLCG1 | |
| SCHEMBL17412904 | 0.77 | BTK (0.49) | BTKITKPLCG1JAK3 | |
| SCHEMBL17413090 | 0.77 | BTK (0.49) | BTKITKPLCG1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016000615-A1 | HETEROARYL COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-07 | — | — | WO | disclosed |