Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5057077 | 0.97 | ABCB1 (0.47) | ABCB1CTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL5062397 | 0.86 | HPGD (0.44) | ABCB1CTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL18091859 | 0.84 | CTNNB1 (0.42) | CTNNB1WNT3ANPC1RAB9AHPGD | |
| SCHEMBL5053961 | 0.83 | ABCB1 (0.52) | ABCB1CTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL9102034 | 0.82 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL5062538 | 0.81 | ABCB1 (0.55) | ABCB1 | |
| SCHEMBL9100621 | 0.80 | ABCB1 (0.47) | ABCB1HPGD | |
| SCHEMBL5057464 | 0.78 | CTNNB1 (0.47) | ABCB1CTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL5053859 | 0.78 | ABCB1 (0.52) | ABCB1HPGD | |
| SCHEMBL5053803 | 0.78 | ABCB1 (0.42) | ABCB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |